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Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies

Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies   Oncologica has participated in a study, led by AstraZeneca, to further improve the tests that are used to pin point the patients most likely to respond to a new type of anti-cancer treatment called […]

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Taking the Oncofocus Test: Karan’s Testimony

Karan Jensen was diagnosed in 2017, aged 48 with cervical cancer. Karan ordered the Oncofocus Test to identify additional treatment options and shares her story here in the following Q&A. How did your diagnosis come about? I had been having regular smear tests, but then one came back with irregular cells and the doctor asked […]

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‘Revolutionary’ new class of cancer drugs approved

A “revolutionary” new class of cancer drug that can treat a wide range of tumours has been approved for use in Europe for the first time. Tumour-agnostic drugs do not care where the cancer is growing in the body as long as it has a specific genetic abnormality inside. UK doctors testing the drugs said […]

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The most precise treatments with genetic tests

Molecular genetic testing identified the most precise treatments Genetic testing not only provides information regarding the chance of developing a particular disease but is also crucial in identifying the most effective anti-cancer therapy for each individual patient suffering from any solid tumour. Thus the battle against the tumour is tailored.   PREVENTION Genetic tests are […]

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Sherrie Hewson’s brother diagnosed with an “incurable” brain tumour now enlisted the help of a special medical company called Oncologica

Sherrie Hewson was due on stage when her phone rang with shattering news. The Coronation Street ­favourite’s beloved elder brother Brett had been diagnosed with an incurable brain tumour. He was given 18 months to live. Sherrie, 68, burst into floods of tears in her dressing room. The actress, who played stroppy hotel manager Joyce […]

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Thousands of Pounds Raised for Mother of Five’s Cancer Treatment

THOUSANDS of pounds have been donated within just two days to help a young Co Donegal mother-of-five access life saving cancer treatment. Sonya Hamilton McCloskey (35) – who is originally from St Johnston close to the Derry border but lives with husband Michael in Ballybofey – has been fighting cancer for the past two years. […]

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What does personalised medicine mean for you?

Source: bbc.com Medicine has always been personal to some extent – a doctor looks for the best way to help the patient sitting in front of them. But with advances in technology, it is becoming possible to use the most unique of characteristics – our genomes – to tailor treatments for individuals. Genomes are made […]

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The Testimony of an Oncofocus Patient

Note: In order to respect the privacy of the patient, his/her identity will not be revealed. I was diagnosed with terminal bowel cancer in March 2018. I started radiotherapy, which worked well. The tumour then started to cause a build up of fluid in my abdomen, which chemotherapy helped to reduce. However, when the first […]

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Using Tumor Genomic Profiling to Guide Treatment Selection Extends Survival in Advanced Sarcoma

The results of a new study, underscoring the value of precision medicine in advanced sarcoma, showed that patients with heavily pretreated sarcoma who received treatment in accord with their mutational profile attained better outcomes than patients who did not (Abstract 11018). Most notably, median overall survival reached 22.1 months for patients treated with agents targeting […]

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Immunotherapy: new hope in the battle against cancer

Immunotherapy is a burgeoning sector that heralds a breakthrough against the world’s second-most deadly disease. Dr Mike Tubbs explains how investors can benefit too. Cancer is the world’s second-biggest killer. The disease is responsible for around one in six deaths globally; 9.6 million people succumbed to it in 2018, while 18.1 million new cases were […]

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Comprehensive Tumor Profiling Promises New Therapeutic Options for Patients with Advanced Cancer

The WINTHER trial***, NCT01856296, led by investigators from Vall d’Hebron Institute of Oncology – VHIO (Spain), Chaim Sheba Medical Center (Israel) (Raanan Berger), Gustave Roussy (France) (Jean-Charles Soria), Centre Léon Bérard (France) (Pierre Saintigny), Segal Cancer Centre, McGill University (Canada) (Wilson H. Miller), UT MD Anderson Cancer Center (USA) (Jordi Rodon and Apostolia-Maria Tsimberidou) and […]

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Genomic Profiling in Sarcoma Shows Potential in Guiding Clinical Management

A new single-center report has found that the results of next-generation sequencing (NGS)–based molecular profiling for non–GI stromal tumor (non-GIST) sarcomas provided information used to effectively guide clinical management. A team of authors led by Spandana Boddu, a research assistant at Moffitt Cancer Center in Tampa, Florida, analyzed data from 114 patients with a diagnosis […]

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